Synthetic studies toward the brasilinolides: controlled assembly of a protected C1–C38 polyol based on fragment union by complex aldol reactions
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چکیده
منابع مشابه
Toward the total synthesis of the brasilinolides: stereocontrolled assembly of a C1-C19 polyol segment.
Two highly convergent syntheses of a fully protected C1-C19 polyol subunit of the brasilinolide family of immunosuppressive macrolides are described, exploiting boron-mediated 1,5-anti aldol couplings to form the C8-C9 and C13-C14 bonds.
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ژورنال
عنوان ژورنال: Organic & Biomolecular Chemistry
سال: 2015
ISSN: 1477-0520,1477-0539
DOI: 10.1039/c5ob00498e